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Friday, December 6, 2013

ATOD & Advocacy Update - Week Ending December 6, 2013



6.8 Million Adults Had Both Mental Illness and Substance Use Disorder in 2011
In 2011, 18.9 million adults in the United States had past year substance use disorder (SUD), and 41.4 million adults had mental illness in the past year; 6.8 million adults experienced both (Figure). Among adults with SUD, 36.1 percent also had a co-occurring mental illness, whereas, among adults without SUD, 16.2 percent had mental illness. Among adults with mental illness in the past year, 16.5 percent had SUD, compared with 6.3 percent of adults who did not have mental illness. Providers working with individuals with either SUD or mental illness may consider screening for co-occurring disorders and linking individuals to integrated treatment programs. For more information on co-occurring mental illness and SUD from the National Survey on Drug Use and Health (NSDUH), please go to: http://www.samhsa.gov/ data/2k13/NSDUH148/ sr148-mental-illness-estimates.htm. Source: National Surveys on Drug Use and Health (NSDUH), 2011 (revised October 2013). NSDUH is an annual survey sponsored by the Substance Abuse and Mental Health Services Administration (SAMHSA). The survey collects data by administering questionnaires to a representative sample of the population through face-to-face interviews at their places of residence. 

Hangovers after 40: Why alcohol packs a more powerful punch as you age
‘All of the effects of alcohol are sort of amplified with age’: Body composition, medication and liver functionality all contribute to longer-lasting hangovers and greater sensitivity to booze, experts say.
Once you hit 40, you may find that drinking like you did in your 20s leaves you feeling worse for wear in the morning. That's because alcohol hits you harder as you get older and everything from muscle mass to over-the-counter meds are to blame for the more painful hangovers. Click here to continue.

Top 17 Abused Prescription Drugs of 2013
The CDC, according to the White House’s website, classifies prescription drug abuse as an epidemic. Many young people who get involved with drugs start with prescription drugs, as they frequently view them as safer than illegal ones because they’re prescribed by doctors. So, which often-abused prescription medicines are the biggest troublemakers? Below is a list of 17 abused prescription drugs as listed by CDC, FDA, the U.S. Drug Enforcement Agency (DEA), and nongovernment nonprofit sources on public websites. More here.

Drug use among U.S. workers down 74% over 25 years since passage of the Drug-Free Workplace Act
Drug use among American workers declined dramatically over the past 25 years, although the rate of positive test results for certain drugs, including amphetamine and opiates, continues to climb, according to a landmark analysis of workplace drug test results by Quest Diagnostics. The special 25th Anniversary Drug Testing Index (DTI) coincides with the passage of the Drug-Free Workplace Act in 1988, which was a catalyst for greater awareness of the problem of workplace drug use and the implementation of workplace drug education and monitoring programs, including drug testing by federal agencies and private employers in the United States. Please click here to read more.

Editorial - Punch-drunk culture must stop celebrating alcohol abuse
The time will have to come when Australia confronts and acts on the damage done by alcohol, just as it did with tobacco.  For the moment, too many people see the abuse of alcohol as someone else’s problem. Tougher government action on prevention is not seen as a priority, especially if that means higher prices, restricted access and a rethink of the central role booze plays in our cultural life. As evidence builds of the immense damage alcohol abuse is causing, let’s hope Australians will begin to see the need for action.   In the past week alone, the Herald has reported how one in eight deaths of Australians aged under 25 is related to alcohol consumption; two in three young drinkers indulge specifically to get drunk; pre-loading of drinks is feeding a culture of binge drinking. This week we can expect the drunken antics of teens at schoolies. Rest of this item is here.

More School, Less Spirit: Why Young People Are Drinking Less Alcohol
College kids on both sides of the Atlantic are drinking much less than they did 30 years ago. But the true teetotalers here are non-college kids.
British undergrads these days are suspiciously sober, says the Financial Times. And pub owners think they know the culprit. It's tuition. The British government decided two years ago to let universities raise tuition fees from £3,375 to £9000. Confronted by tighter budgets and poorer post-graduation job prospects, students have traded beers for books. "Nine thousand pounds is a sobering enough number for anybody," the chief executive of Britain's biggest nightclub operator told the paper. Continue reading here.

1 in 6 unemployed are substance abusers
About 1 in 6 unemployed workers are addicted to alcohol or drugs -- almost twice the rate for full-time workers, according to the government's National Survey on Drug Use and Health. The survey shows that 17% of unemployed workers had a substance abuse disorder last year, whereas 9% of full-time workers did so. The numbers are self-reported, and therefore, could be even higher in reality. Please click here for the rest of this story.

Study deems US alcohol ad regulations ‘ambiguous’
Academics from the John Hopkins Bloomberg School of Public Health in Baltimore found that the majority of spirits advertisements in magazines across the US adhered to industry regulations, but added concerns that these rules are often “ambiguous” Katherine Smith, associate professor at the college and lead author of the paper, told Reuters: “In our paper one of our main findings is that the content is largely adherent to federal and industry codes, but it’s still very problematic.” In particular, Smith notes that sexual representation in these advertisements may not be subject to clear guidelines and that “compliance is largely a non-issue” due to the blurred definition of standards. Click here to continue.

5 Jaw-Dropping Facts about Legal Marijuana
The legal use of marijuana for both medical use and adult recreational use is on the rise. Here are five facts that might just surprise you about the drug. Rest of this story continues here.

Why Family Dinners Won't Stop Drug Abuse
Researchers doubt whether meals keep teenagers from substance abuse.
Food-fueled family gatherings at Thanksgiving undoubtedly are a boon for turkey farmers, football broadcasters and airlines. Do they also keep teenagers from using drugs and alcohol? The role of family dinners in preventing substance abuse has become a surprisingly fertile field of research. For a decade, an organization affiliated with Columbia University has reported on the result of asking teenagers about how often they eat dinner with their families, as well as their use of, and attitudes toward, drugs, tobacco and alcohol. The surveys' consistent finding, that the most frequent family diners are the least frequent drug abusers, has been trumpeted in many news articles touting the benefits of family meals. The finding was satisfying to family-values advocates and, in the view of many, consistent with common sense. The idea that family dinners protect teens "conjures up Norman Rockwell images of families seated around the table together," said Daniel P. Miller, assistant professor of human behavior at the Boston University School of Social Work. "It plays into what we think a family ought to look like." Some researchers, however, including Dr. Miller, were skeptical, wondering if other factors, such as a family's income or parents' weekly work hours, accounted for both the frequency of family meals and drug use. Or maybe, these researchers said, the conclusion that such dinners suppress drug use mixes up cause and effect: Teens out misbehaving with their friends might not get home in time for dinner, for example. Please click here to continue.

Report: Only Half of Prescription Drugs Removed From Sewage by Treatment Plants
A report by U.S. and Canadian officials concludes only about half of prescription drugs and other “chemicals of emerging concern” are removed from sewage by treatment plants. The findings come from the International Joint Commission, a group of officials studying the Great Lakes. Better water treatment is needed, the report concludes. “The compounds show up in low levels – parts per billion or parts per trillion – but aquatic life and humans aren’t exposed to just one at a time, but a whole mix,” said study lead author Antonette Arvai. “We need to find which of these chemicals might hurt us.” The researchers analyzed 10 years of data from wastewater treatment plants around the world, to see how effective they are at removing 42 compounds increasingly being detected in the Great Lakes, Scientific American reports. Six of the compounds were detected frequently, and had a low rate of removal in treated sewage. Five of the six were drugs: an anti-seizure medication, two antibiotics, an antibacterial drug and an anti-inflammatory drug. The sixth compound was an herbicide. Diana Aga, a chemistry professor and researcher at the University of Buffalo who studies emerging chemicals in the Great Lakes, told the magazine that even without knowing the impact of the drugs in treated sewage, it is concerning to see antibiotics showing up. “Even at low levels you don’t want to have people ingest antibiotics regularly because it will promote resistance,” she said.

Heavy Drinking Can Dry Up a Marriage If One Spouse Abstains
Heavy drinking by one partner in a marriage increases the risk of divorce, but that's not the case if both spouses are heavy drinkers, a new study finds. Researchers followed nearly 650 couples for the first nine years of their marriage and found that the divorce rate was nearly 50 percent for couples where only one partner drank heavily. Heavy drinking was defined as having six or more drinks at one time or drinking to intoxication. The divorce rate for couples where neither were heavy drinkers and for couples where both were heavy drinkers was 30 percent, according to the study, published in the December issue of Psychology of Addictive Behaviors. You can continue reading this story here.

Chris Christie says no to bill expanding medical marijuana program
The latest bill to expand the medical marijuana program is only days old, but Gov. Chris Christie said he already knows he won't sign it. The bill would allow registered medical marijuana patients in New Jersey to buy the drug in another state where it's legal and bring it home. Six of the 19 states and Washington D.C. that have medical marijuana programs have such reciprocity agreements by which they recognize patients outside of their own state. Christie told reporters he is "not open to it," and believes it's just a back door way to legalize marijuana for everyone. Continue reading here.

Molly ER Visits Rose 128 Percent in Six Years Among Those Under 21
Emergency room visits related to Molly, or Ecstasy, rose 128 percent among people younger than 21 between 2005 and 2011, according to a new government report. The number of visits by young people to U.S. emergency rooms for complications from Molly increased from 4,460 to 10,176, CBS News reports. “I think people are looking for the ultimate and safe high they can achieve,” said Dr. Robert Glatter, an emergency room physician at Lenox Hill Hospital in New York. “There’s a mistaken belief that this is a safe drug with little toxicity.” The drug, also known as MDMA, is usually taken in pill or powder form. It is sometimes mixed with substances such as cocaine, heroin or ketamine, the article notes. Glatter warned the drug can be even more dangerous if it is mixed with alcohol. “There’s a greater potential effect of toxicity,” he added. “Patients want to combine the two substances and have a greater effect that in and of itself is much more dangerous considerably.” According to the Substance Abuse and Mental Health Services Administration, which released the report, Molly can produce a variety of undesirable health effects such as anxiety and confusion, which can last one week or longer after using the drug. Other serious health risks associated include becoming dangerously overheated, high blood pressure, and kidney and heart failure.
“This should be a wake-up call to everyone, but the problem is much bigger than what the data show,” said Steve Pasierb, president and CEO of The Partnership at Drugfree.org. “These are only the cases that roll into the emergency rooms. It’s just the tip of the iceberg.”

6 Percent of Teens Report Using Psychiatric Medicine: Report
A new government report finds about 6 percent of U.S. teens say they use a psychiatric medicine as drug therapy, similar to the rate 10 years ago. Boys are more likely than girls to be prescribed stimulants such as Ritalin for attention deficit hyperactivity disorder (ADHD), while girls are more likely to be given antidepressants, Bloomberg reports. ADHD drugs and antidepressants were the most commonly prescribed medicines for teens between 2005 and 2010, according to the report by the Centers for Disease Control and Prevention. A survey of teens conducted between 1988 and 1994 found 1 percent of teens were prescribed psychiatric medications. A decade later, 6.8 percent of teens reported using psychiatric drugs to treat a mental health condition, a rate that has held steady since, according to Bruce Jonas, an author of the new study. He noted prescriptions for psychiatric drugs may have risen because of an increased awareness of mental illness among teens, and the availability of new treatments for depression and ADHD. The new survey found about half of teens who reported using psychiatric drugs had seen a mental health professional in the past year. Most of the teens surveyed said they were taking no more than one psychiatric drug. The findings are published in a National Center for Health Statistics Data Brief.

People Who Abuse Prescription Opioids Prefer Oxycodone Over Hydrocodone
A study of opioid-dependent patients entering drug-treatment programs across the country finds oxycodone is the most popular prescription opioid to abuse because of the quality of the high the drug produces. Overall, 75 percent of people who abuse prescription opioids use either oxycodone or hydrocodone, Science Daily reports. The study of 3,520 people who abused opioids found 44.7 percent of patients preferred oxycodone, while 29.4 percent preferred hydrocodone. Ninety percent said they used opioids to alter their mood, while 50 of oxycodone users and 60 percent of those using hydrocodone said they also used the drugs to treat pain. The findings are published in the journal Pain. “The data show that hydrocodone is popular because it is relatively inexpensive, easily accessible through physicians, friends, and families, and is perceived as relatively safe to use, particularly by risk-averse users,” researcher Theodore J. Cicero, PhD, of the Department of Psychiatry at Washington University in St. Louis, said in a news release. “This group includes generally risk-averse women, elderly people, non-injectors, and those who prefer safer modes of acquisition than dealers, such as doctors, friends, or family members. In contrast, we found that oxycodone is much more attractive to risk-tolerant young male users who prefer to inject or snort their drugs to get high and are willing to use riskier forms of diversion despite paying twice as much for oxycodone than hydrocodone.” The researchers noted people who abuse oxycodone are more likely to tamper with the drug in order to inhale or inject it, compared with those who use hydrocodone. While the introduction of an abuse-deterrent formulation of OxyContin in 2010 led to a significant decrease in abuse of the drug, oxycodone products remain more popular than hydrocodone products among people who abuse opioids, they said.

SBIRT: Stopping Addiction Before it Starts
The facts are clear: in our country, there is an imminent need for substance abuse prevention and intervention as early in the teen years as possible. A recent study in the Archives of General Psychiatry found that the 15 percent of U.S. high school students who abuse drugs and alcohol began using at 14 or 15. “When the first exposure occurs in younger versus older adolescents,” explains Professor Didier Jutras-Aswad of the University of Montreal, “the impact…seems to be worse in regard to many outcomes such as mental health, education attainment, delinquency and ability to conform to adult roles.” We know that kids who do not develop an addiction problem by age 21 are unlikely to become addicted later on. Plus, the adolescent brain continues to develop judgment and the ability to resist foolish or dangerous behavior until around age 25, which means that the teen and young adult years are a particularly vulnerable time for the risk-taking that often characterizes them. Please click here to read more.

Medical marijuana reciprocity 'will not happen' in N.J., Christie vows
A measure proposed by New Jersey Assemblywoman Linda Stender calls for allowing residents enrolled in the state's medical marijuana program to purchase medical marijuana out of state. But Gov. Chris Christie said Monday he will not expand the program. "Here's what the advocates want: They want legalization of marijuana in New Jersey. It will not happen on my watch, ever," he said. "I am done expanding the medical marijuana program under any circumstances. Continue reading here.

About 1 Percent of Anesthesiology Residents Have Substance Use Disorder: Study
Slightly less than 1 percent of anesthesiology residents in the United States have a substance use disorder, according to a new study. The incidence of substance use has been increasing, and relapse rates are not improving, the researchers said. The study followed 45,000 anesthesiology residents who began their training between 1975 and 2009, HealthDay reports. They found the overall rate of substance abuse was 0.86 percent. Rates were higher at the beginning of the study, and decreased between 1996 and 2002. They began rising again in 2003. Twenty-eight anesthesiology residents died due to substance abuse during the study period. Among others who abused substances, 43 percent had at least one relapse over the following 30 years, and 11 percent died from a substance use disorder. The most commonly abused substances were intravenous opioids, alcohol, marijuana, cocaine and anesthetics/hypnotics. The findings are published in the Journal of the American Medical Association.

Designer Drugs Imported Legally in Large Quantities
Large amounts of designer drugs are being imported into the United States legally, CBS News reports. The drugs include synthetic marijuana, known as Spice. Drug Enforcement Administration Special Agent Doug Coleman says China is the main source of these drugs. CBS News found a Chinese manufacturer online that sells chemical compounds. The company offered to ship two pounds of synthetic marijuana for $2,500. While Spice and several other synthetic drugs were outlawed by the federal government last year, chemists have been evading the law by continually coming up with chemical compounds that are slightly different from the ones that have been banned. Coleman says U.S. Customs authorities cannot stop imports of compounds that are still legal. “It’s like whack a mole,” he told CBS News. “They pop their head up, we hit them, they go down and then they pop their head up in another spot. It’s always a cat-and-mouse game. This is just a more advanced type of cat-and-mouse because now we’ve got chemists manufacturing synthetic drugs as opposed to cartel members trafficking heroin, or coke, or methamphetamine.” Another synthetic drug that has been growing in popularity is Molly, or Ecstasy. Emergency room visits related to Molly rose 128 percent among people younger than 21 between 2005 and 2011, according to a new government report.

The World’s Deadliest Drug: Inside a Krokodil Cookhouse
About a decade ago, Russian doctors began to notice strange wounds on the bodies of some drug addicts—patches of flesh turning dark and scaly, like a crocodile’s—in the hospitals of Siberia and the Russian Far East. It didn’t take them long to discover the cause: the patients had begun injecting a new drug they called, predictably, “krokodil.” (Some accounts suggest the name was derived from one of the drug’s precursor chemicals, alpha-chlorocodide.) Videos showing the effects of the “flesh-eating” drug—christened desomorphine when it was invented for medical use in 1932—quickly went viral online. There are now alarming stories that the monster could be at large in the U.S. Rest of this photo essay is here.

The Washington Post Editorial: NIH research is ailing from the budget squeeze
Francis S. Collins, director of the National Institutes of Health (NIH), has been distributing a chart that shows the success rate of grant applications to NIH for scientific research. While the rate was about 30 percent as recently as a decade ago, it has plunged to about 15 percent, which Dr. Collins says is the lowest in history. One reason for this is that more applicants are seeking funds, but the budget squeeze also is to blame. Dr. Collins is worried that the low success rate will cause young scientists and researchers to abandon the laboratory for other careers or to take their talents and ideas to other countries. NIH is the source of about 90 percent of basic research funding in biomedicine in the United States, and the field today is exciting and dynamic: Advances in genomics and imaging technologies are throwing open new worlds of exploration and promising vastly greater understanding of how diseases occur and can be treated. This is a time of promise, Dr. Collins told us, in research to fight cancer, HIV/AIDS, influenza and Alzheimer’s disease, among others. The United States should be at the forefront of this era and must pay for the research to do it. From fiscal 1998 to 2003, NIH saw its program-level funding double, then plateau — which, given inflation, really means a steady erosion. More painful budget cuts could be in the offing in January. The argument that biomedical research pays a generous return on investment is well-grounded, not only in dollars but also in lives saved and illnesses conquered. There’s been a serious investment in training a new generation of scientists; it would be a pity to reverse direction on them now. Dr. Collins’s appeal is one among many voiced lately by special interests. Non-defense discretionary spending is being crammed into ever smaller space because of the continuing impasse over the big issues of entitlements, taxes and defense. This affliction in our politics cannot be cured by science or medicine. It will require willpower and difficult choices by the president and Congress. But when the scientist in charge of the nation’s research enterprise frets about “deep long-term damage” to biomedical research, we ought to pay particular attention. The research NIH funds is precisely what we should demand from government. It is critical to our future as a healthy society and world leader in science, and it’s not something the private sector will do in government’s stead. Do political leaders really want to explain to future generations why they let the United States walk away from a great age of biomedical discovery? 

Use of E-Cigarettes Among Teens Linked to Heavier Use of Regular Cigarettes
A new study finds the use of e-cigarettes among teens is associated with heavier use of regular cigarettes. The researchers say their findings suggest that the devices are creating a new pathway for youth to become addicted to nicotine. Researchers at the University of California, San Francisco, studied 75,000 South Korean teenagers. They found four out of five teens who use e-cigarettes also smoke tobacco cigarettes, according to the San Francisco Chronicle. Young e-cigarette smokers were more likely to have tried to quit smoking, which the researchers say suggests that some teens may be using e-cigarettes to try to quit smoking regular cigarettes. “Use of e-cigarettes is associated with heavier use of conventional cigarettes, which raises the likelihood that actual use of e-cigarettes may increase harm by creating a new pathway for youth to become addicted to nicotine and by reducing the odds that an adolescent will stop smoking conventional cigarettes,” the researchers wrote in the Journal of Adolescent Health.

Five Things You Don't Know About Alcohol
On Dec. 5, 1933, the United States ratified the 21st amendment to the U.S. Constitution, ending more than a decade of Prohibition. Federal law still bans the distilling of spirits in the home with numerous licensing requirements. Click here to continue.

Coming soon: A preview of a new, legal marijuana landscape in the U.S.
Mark Kleiman is a UCLA public professor and a go-to guy when it comes to drug policy analysis; it’s a field he’s studied for years, including the consequences and mechanics of the pendulum swings of criminalizing and legalizing marijuana. Lately, the goalposts — at least from the point of view of the legal marijuana lobby — have moved, and Kleiman consulted with Washington state’s liquor control board about the rules of the road for the state’s Jan. 1 legal marijuana market. He’s been assessing law enforcement and marijuana in the evolving legal marijuana world. He’d told Washington state that legalizing didn’t mean not policing in the new marijuana market; it may in fact require more at the outset, to make certain the new rules are followed and an illicit market doesn’t persist. Read on here.

Friday, November 22, 2013

ATOD & Advocacy Update - Week Ending November 22, 2013



Zohydro to be Manufactured by Same Company That Makes Addiction Medicine
The newly approved pure hydrocodone product, Zohydro ER (extended release), will be made by the same company that manufactures Vivitrol, a drug used to treat patients addicted to opioids or alcohol, The New York Times reports. The Food and Drug Administration (FDA) approved Zohydro ER last month for patients with pain that requires daily, around-the-clock, long-term treatment that cannot be treated with other drugs. Drugs such as Vicodin contain a combination of hydrocodone and other painkillers such as acetaminophen. Zohydro is expected to reach the market in early 2014. In December 2012, a panel of experts assembled by the FDA voted against recommending approval of Zohydro ER. The panel cited concerns over the potential for addiction. In the 11-2 vote against approval, the panel said that while the drug’s maker, Zogenix, had met narrow targets for safety and efficacy, the painkiller could be used by people addicted to other opioids, including oxycodone. In 2010, Zogenix bought the right to market Zohydro in the United States from another company, Elan, the article notes. The following year, a company named Alkermes, which makes Vivitrol, bought a unit of Elan that included Zohydro. The deal included the existing agreement with Zogenix. Some law enforcement agencies and addiction experts have voiced concern that approval of a pure hydrocodone drug will lead to an increase in overdoses.

PCP-Related Visits to the Emergency Room Jumped 400% Between 2005 and 2011
PCP-related emergency room visits jumped 400 percent between 2005 and 2011, according to a new report by the Substance Abuse and Mental Health Services Administration (SAMHSA). PCP (phencyclidine), also known as “angel dust,” can cause hallucinations when taken at high doses. The number of PCP-related visits to hospital emergency rooms jumped from 14,825 in 2005, to 75,538 in 2011, Medical News Today reports. The largest increase was seen among patients ages 25 to 34. In 2011, about two-thirds of PCP-related visits were made by males, and almost half were made by people ages 25 to 34. Other illegal drugs, including marijuana, cocaine and heroin, were involved in about half of PCP-related emergency room visits in 2011. PCP can be snorted, smoked, injected, or swallowed and is most commonly sold as a powder or liquid and applied to a leafy material such as mint, parsley, oregano, tobacco, or marijuana. Many people who use PCP may do it unknowingly because it is often used as an additive and can be found in marijuana, LSD, or methamphetamine. In a hospital or detention setting, a person on PCP may become violent or suicidal, and can become very dangerous to themselves and to others. “This report is a wake-up call that this dangerous drug may be making a comeback in communities throughout the nation,” Dr. Peter Delany, Director of SAMHSA’s Center for Behavioral Health Statistics and Quality, said in a news release. “PCP is a potentially deadly drug and can have devastating consequences not only for individuals, but also for families, friends and communities. We must take steps at every level to combat the spread of this public health threat.”

Addiction Treatment with a Dark Side
In Demand in Clinics and on the Street, ‘Bupe’ Can Be a Savior or a Menace.
For Shawn Schneider, a carpenter and rock musician, the descent into addiction began one Wisconsin winter with a fall from a rooftop construction site onto the frozen ground below. As the potent pain pills prescribed for his injuries became his obsessive focus, he lost everything: his band, his job, his wife, his will to live. Mr. Schneider was staying in his parents’ basement when he washed down 40 sleeping pills with NyQuil and beer. His father heard him gasping and intervened, a reprieve that led Mr. Schneider into rehab, not his first program, but the one where he discovered buprenorphine, a substitute opioid used to treat opioid addiction. In the two years since, by taking his “bupe” twice daily and meeting periodically with the prescribing psychiatrist, Mr. Schneider, 38, has rebounded. He is sober, remarried, employed building houses, half of a new acoustic duo and one of the many addicts who credit buprenorphine, sold mostly in a compound called Suboxone, with saving their lives. Continue reading here.

The benefits and health risks of beer and wine
More than a few baby boomers imbibed too much during their misspent youth, leaving them with a lifelong apprehension of what can come from drinking alcohol. But a raft of medical studies over the past generation shows that alcohol has proven health benefits, provided you drink in moderation — one or two drinks a day, three or four days a week. Many doctors say the findings are no longer in doubt, even if some boomers with long memories continue to be skeptical. “There’s no question that people who drink moderately have lower rates of heart attacks, lower rates of diabetes, and live longer,” said Dr. Eric Rimm, associate professor in the departments of epidemiology and nutrition at the Harvard School of Public Health in Boston. “If you ask most cardiologists, they would say drinking in moderation is beneficial.” Even more interesting: People who only drink occasionally, or on weekends, aren’t likely to enjoy the same health benefits as those who drink every other day, Rimm suggested. Alcohol reduces the risk of blood clotting in the 24 hours after drinking, for example, but not in the days after. Other benefits, such as a rise in good cholesterol, making it easier to process glucose, are more likely to extend throughout the week. Please click here to continue reading.

Alcohol Has Bigger Effect on People in Middle Age Due to Physical, Lifestyle Changes
Alcohol affects people more in middle age due to physical and lifestyle changes, according to The Wall Street Journal. As people start to take more medication in their 40s and 50s, the risk of alcohol and drug interactions also increases. As people reach middle age, they experience changes in body composition, brain sensitivity and liver functioning, the article notes. “All of the effects of alcohol are sort of amplified with age,” David W. Oslin, a professor of psychiatry at the Perelman School of Medicine at the University of Pennsylvania, told the newspaper. “Withdrawal is a little bit more complicated. Hangovers are a little bit more complicated.” Changes in body composition during middle age result in more alcohol circulating in the bloodstream. In addition, the liver, which metabolizes alcohol, gets less efficient as people age. The level of certain enzymes that break down alcohol decreases. Hormonal changes that women experience during menopause can increase their sensitivity to alcohol. In middle age, people tend to drink less than they did when they were younger, notes Robert Pandina, director of the Center of Alcohol Studies at Rutgers University. So when you do drink “you might have a more sensitive response to alcohol because you’ve lowered your exposure to alcohol over all,” he said. Drugs that can interact with alcohol include heartburn drugs such as Zantac, acetaminophen, and blood thinners like Coumadin. Mixing blood thinners with alcohol can cause bleeding. “People on Coumadin shouldn’t really drink at all,” Dr. Oslin noted. Combining alcohol with some pain medications and benzodiazepines can make a person “more prone to sedation, more prone to cardiovascular risk and more prone to overdose,” he added. According to the Centers for Diseases Control and Prevention, about 52 percent of people ages 45 to 64 had at least 12 drinks in the previous year.

Senate Passes Measure Establishing System to Track Prescription Drugs
The U.S. Senate this week passed a measure that will establish a system to track prescription drugs from the time they are manufactured until they are sold at a drugstore, The News & Observer reports. The bill awaits President Obama’s signature. Over the next seven years, The Drug Quality and Security Act calls for drug manufacturers, repackagers, wholesale distributors and dispensers to pass and hold onto key information about each drug’s distribution history. The goal is to allow unit-level product tracing within 10 years. Four years after the law is enacted, manufacturers will serialize drugs in a consistent way across the industry, to allow for efficient tracing to respond to recalls and notices of theft and counterfeiting. “This legislation will improve the safety of compounded drugs as well as establish an unprecedented tracing system that will, for the first time ever, track prescription drugs from manufacturing to distribution, thereby thwarting drug counterfeiters,” Senate Health, Education, Labor, and Pensions Committee Chairman Tom Harkin of Iowa said in a news release. “Americans must have the confidence that their drugs—whether obtained at a hospital, at a doctor’s office, or at the pharmacy counter—are safe, and that is exactly what this bill does.” John Castellani, President and CEO of the Pharmaceutical Research and Manufacturers of America, said in a statement, “The counterfeiting of prescription drugs is on the rise within the United States but oftentimes goes unnoticed or unreported, leaving many Americans unaware of this problem. In fact, some experts have cited the counterfeiting of these medicines as even more lucrative than the trafficking of illegal drugs like heroin and cocaine. This act will improve the security of the finished drug supply chain and reduce the impact of the patchwork of state laws related to the pedigree requirements for drug distribution.”

Poison Control Experts Warn of Danger From Detergent Capsules That Look Like Candy
Poison control experts are warning parents about single-dose detergent capsules that look like candy. These products were involved in about 10,000 cases of exposure involving young children, The Wall Street Journal reports. “Some children who have gotten the product in their mouths have had excessive vomiting, wheezing and gasping,” the American Association of Poison Control Centers notes on its website. “Some get very sleepy. Some have had breathing problems serious enough to need a ventilator to help them breathe. There have also been reports of corneal abrasions (scratches to the eyes) when the detergent gets into a child’s eyes.” Last year, single-dose detergent pods became popular, the article notes. Thousands of children who ate or otherwise came into contact with laundry pods received medical attention. Some had breathing problems that required days of hospitalization. A 7-month-old boy in Florida died in August after eating a laundry detergent capsule. Proctor & Gamble, which makes Tide Pods, was warned about possible problems three years ago by officials at an Italian poison control center. They contacted the company to report children were biting into small packets of the company’s concentrated liquid detergent called Dash Ecodosi. The poison control officials recommended making the capsules’ packaging opaque, and more difficult to open. After the company made the changes, reported poison cases fell by 60 percent over six months, according to the newspaper. While Proctor & Gamble studied the problem in Italy, it launched Tide Pods in the United States and Canada in clear containers. The company said it wanted to see whether making the packages opaque worked before trying them in North America. It changed the packaging in the United States and Canada this past spring. Clear packages are now largely phased out.

Office of the National Coordinator to help fight Rx drug abuse
Developing standards to bring prescription info from state databases into EHRs and HIEs
In an effort to combat the prescription drug abuse epidemic, the Office of the National Coordinator (ONC) has launched a new interoperability initiative to better link drug monitoring programs with health IT systems. In a blog post, Jennifer Frazier, ONC's behavioral health subject matter expert, says the new Standards & Interoperability Framework Initiative seeks to solve problems related to the lack of common technical standards and vocabularies that could help prescription drug monitoring programs "share computable information" with health IT systems. The PDMP & Health IT Integration framework "will bring together the PDMP and heath IT communities to establish a standardized approach to retrieve data stored in the PDMPs and deliver it to EHRs and HIEs," Frazier writes. Finding a better way to give care providers easy access to PDMP data "can't happen quickly enough, as clinicians across the country struggle to fight a growing national public health crisis," she adds. "Opioid painkillers, such as hydrocodone and oxycodone, are typically the most abused drugs. Patients are prescribed these drugs to help manage pain from injury or surgery. When taken as prescribed, these medications are generally safe; but when misused or abused, they can be highly addictive – even deadly." Please click here to continue.

New study identifies spiritual change among adolescents in treatment
A research team hopes that its latest study of factors that influence good outcomes in adolescents with substance use problems will lead more clinicians and programs to take a second look at spiritually based treatment approaches for youths. The study, which will be published next spring in Alcoholism Treatment Quarterly, found that daily spiritual experiences (encompassing more than formal religious practices alone) served as a strong predictor of sobriety in a youth population with complex problems. Strikingly, while one-third of study participants had self-identified as agnostic or atheist at the start of the study, two-thirds of those individuals would claim some spiritual identity two months later, after receiving substance use treatment. Continue here.

The bottom of the bottle: Alcoholism still tough to treat in an era of craft liquor
Evanston’s first craft brewery, Temperance Beer Company, started churning out batches of booze earlier this year; its first craft whiskey distillery, FEW Spirits, just won a $250,000 loan from the town for an expansion project. With 409 craft breweries opening in the U.S. in 2012 alone and five times as many U.S. micro-distilleries in 2012 as in 2005, it’s clear that the small-batch liquor industry is booming. For some people, however, one sip of alcohol is a sip too many. Read on here.

Researchers identify a group of 39 genes linked with alcoholism
There is good evidence from studies of families and twins that genetics plays an important role in the development of alcoholism. However, hundreds of genes likely are involved in this complex disorder, with each variant contributing only a very small effect. Thus, identifying individual risk genes is difficult. Using a new approach that combines genome-wide association studies (GWAS) with information about which human proteins interact with one another, researchers from the University of Iowa and Yale University Medical School have identified a group of 39 genes that together are strongly associated with alcoholism. "The discovery of these genes may open a new window into the biological mechanisms underlying this alcoholism disorder," says Shizhong Han, PhD, UI assistant professor of psychiatry and corresponding author of the study, which was published Nov. 21 in the American Journal of Human Genetics. "Eventually, it's our hope that the findings might help to develop drugs to treat or prevent this disorder." Han and his colleagues based their approach for identifying risk genes on the idea that genes may be "guilty by association" of contributing to the disease -- that although many different genes contribute to alcoholism, these genes, or more precisely, their protein products, are not independent of each other. "The proteins made by these genes could be neighbors, or they could be part of the same functional biological pathway," Han explains. "We took advantage of their biological relatedness to identify a network of genes that interact and together contribute to the susceptibility to alcoholism." The team conducted the study by using two large data sets collected for the genetic study of addiction -- the Collaborative Study on the Genetics of Alcoholism (COGA) and the Study of Addiction: Genetics and Environment (SAGE). These data sets document genome-wide common variants information from several thousand people linked to information about these individuals' alcohol dependence or other types of addiction\. The research team analyzed the merged SAGE and COGA datasets for genetic variants associated with alcoholism. No single variant was strongly associated with the condition, but when the researchers integrated information about protein-protein interactions from the Human Protein Interaction Network, they identified a network of 39 genes that was not only enriched for alcoholism-associated genes, but also was collectively strongly associated with alcoholism. This strong association held for both European Americans and African Americans. Furthermore, the team was able to replicate the finding in three additional genetic datasets, two of individuals of European ancestry and one of individuals of African ancestry, suggesting that the findings are robust. To minimize the possibility of the result being a false positive, the researchers also analyzed the gene network for associations with other complex human diseases - bipolar disorder, depressions and diabetes. The gene network was not associated with any of these conditions. In addition to finding the highly statistically significant association between the gene network and alcoholism, many of the genes identified also appear to be biologically relevant to brain processes likely to be affected in alcoholism. For example, the network contains genes for ion channel proteins that appear to be involved in tolerance toward some of the physiological effects of alcohol. Other genes code for proteins involved in general brain processes, including synaptic transmission, ion transport, and transmission of nerve impulses.

Drug testing is a great idea. Thanks, Rep. Radel.
Rep. Trey Radel voted in favor of drug-testing the folks who get food stamps. In that case, why don’t we drug-test all people who get federal money? Let’s start with members of Congress! Radel, the Florida Republican whose campaign was heavy on balancing the budget, would be the first to save the government some money on that plan. The 37-year-old congressman who describes himself on Twitter as a “Hip Hop Conservative” — whatever that is — lasted just 10 months in the nation’s capital before his Nose Snow Rewards Card balance tripped the radar of law enforcement. He was busted last month after buying $250 worth of cocaine from a federal agent. And it apparently wasn’t his first time on this particular sleigh ride. Continue reading here.

What’s So Bad About Casual Drug Use?
Most people who try cocaine don't go on to become addicts
So Representative Trey Radel, the Republican from Florida, a self-styled “conservative voice” in Congress, has pleaded guilty to a misdemeanor charge of cocaine possession. And Toronto’s city council has stripped Mayor Rob Ford of much of his power after it came out that he had smoked crack (never mind that Ford’s well-known drunken antics were not cause for such censure). Rather than arguing whether such figures are hypocrites (Radel voted in favor of mandatory drug testing for food-stamp beneficiaries) or debating how they should attempt damage control (he’s also pledged to enter a substance-abuse program after paying a fine and receiving a year’s probation), let’s ask a more basic question: What’s so scandalous about casual drug use?  Continue reading here.

More Than Half of Teens With Mental Health Disorders Do Not Receive Treatment: Study
More than half of teens in the United States who have mental health disorders do not receive treatment, according to a new study. The findings come from an analysis of more than 10,000 teens. Of those teens who do receive help, most are not treated by a mental health professional, HealthDay reports. They are treated by pediatricians, school counselors or probation officers. “It’s still the case in this country that people don’t take psychiatric conditions as seriously as they should,” lead researcher E. Jane Costello of Duke University said in a news release. “This, despite the fact that these conditions are linked to a whole host of other problems.” Overall, in the past year, 45 percent of teens with psychiatric disorders received some form of service. The most likely to receive help were those with attention deficit hyperactivity disorder (74 percent), conduct disorder (73 percent) or oppositional defiant disorder (71 percent). Those least likely to receive services were those with phobias (41 percent) and any anxiety disorder (41 percent). Black teens were much less likely than white teens to receive mental health treatment. There are not enough qualified pediatric mental health professionals in the United States, Costello said. “We need to train more child psychiatrists in this country,” she noted. “And those individuals need to be used strategically, as consultants to the school counselors and others who do the lion’s share of the work.” The findings appear in the journal Psychiatric Services.